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Magnetic resonance surgery using heat waves produced with focussed ultrasound

Patent 5291890 Issued on March 8, 1994. Estimated Expiration Date: Icon_subject August 29, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Patent #: 4646756
Issued on: 03/03/1987
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Apparatus for examining and localizing tumors using ultra sounds, comprising a device for localized hyperthermia treatment
Patent #: 4658828
Issued on: 04/21/1987
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Non-surgical method for suppression of tumor growth
Patent #: 4671254
Issued on: 06/09/1987
Inventor: Fair

Localized heat applying medical device
Patent #: 4773413
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Non-invasive tissue thermometry system and method
Patent #: 4807633
Issued on: 02/28/1989
Inventor: Fry

More ...

Inventor

Application

No. 751259 filed on 08/29/1991

US Classes:

600/411, Combined with therapeutic or diverse diagnostic device600/412, Temperature detection601/3, Hyperthermia601/15With light, thermal, magnetic, or electrical application

Examiners

Primary: Cohen, Lee S.
Assistant: Pfaffle, Krista M.

Attorney, Agent or Firm

Foreign Patent References

  • 8907907 EP. 09/13/1989
  • 9002343 EP 03/13/1990
  • 3931854 DE. 04/13/1991

International Class

A61B 005/055

Abstract

Surgery is performed with pulsed heat means that selectively destroys tissue in a region within a patient. The size of the region destroyed is dependent upon the frequency of the pulses of the pulsed heat means and thermal conductivity of the tissue of the patient. The pulsed heat means can be a coherent optical source that is guided by laser fiber to the tissue to be destroyed. In another embodiment the pulsed heat means is a focussed ultrasound transducer that dissipates ultrasonic energy at a focal point within the region of tissue to be destroyed. A magnetic resonance imaging system employing a temperature sensitive pulse sequence creates an image of the tissue and the region being heated to allow a surgeon to alter the position of the pulsed heat means or vary the pulse frequency.

Other References

  • F. A. Jolesz, A. R. Bleire, P. Jakob, P. W. Ruenzel, K. Huttl, G. J. Jako. "MR Imaging of Laser-Tissue Interactions." Radiology (1968), vol. 168, p. 249
  • B. E. Billar, K. Hynynen, P. B. Roemer. "Effects of Physical Parameters of High Temperature Ultrasound Hyperthermia." Ultrasound in Med. & Biol. (1990), vol. 16, No. 4, pp. 409-420
  • T. R. Anthony, W. F. Banholzer, J. F. Fleischer. "Thermal Diffusity of Isotopically Enriched 12 C Diamond." Physical Review B, Jul. 15, 1990, vol. 42, No. 2, pp. 1104-1111
  • H. S. Carlsow and J. C. Jaeger, "Conduction of Heat in Solids". 2nd Edition, 1959, Oxford, Clarendon Press, pp. 64-68
  • Denis LeBihan, Jose Delannoy, Ronald L. Levin, "Temperature Mapping with MR Imaging of Molecular Diffusion: Application to Hyperthermia," Radiology 1989, vol. 171, pp. 853-85
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