Diltiazem formulation

Patent 5286497 Issued on February 15, 1994. Estimated Expiration Date:

May 6, 2013. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

Captopril and diltiazem composition and the like
Patent #: 4871731
Issued on: 10/03/1989
Inventor: Walker

Diltiazem formulation
Patent #: 4891230
Issued on: 01/02/1990
Inventor: Geoghegan, et al.

Controlled absorption diltiazem formulation for once-daily administration
Patent #: 4894240
Issued on: 01/16/1990
Inventor: Geoghegan, et al.

Controlled absorption diltiazem formulation
Patent #: 4917899
Issued on: 04/17/1990
Inventor: Geoghegan, et al.

Controlled absorption diltiazem formulations
Patent #: 5002776
Issued on: 03/26/1991
Inventor: Geoghegan, et al.

Sustained release pharmaceutical composition of diltiazem
Patent #: 5112621
Issued on: 05/12/1992
Inventor: Stevens, et al.

Sustained release diltiazem formulation Patent #: 5229135
Issued on: 07/20/1993
Inventor: Philippon, et al.

Inventors

Assignee

Carderm Capital L.P.

Application

No. 058534 filed on 05/06/1993

US Classes:

424/490, Coated (e.g., microcapsules)424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/497Containing solid synthetic polymers

Examiners

Primary: Page, Thurman K.
Assistant: Benston, William E. Jr.

Attorney, Agent or Firm

Killworth, Gottman, Hagan & Schaeff

Foreign Patent References

193164 EP. 02/13/1986
225085 EP. 11/13/1986
282698 EP. 01/13/1988
320097 EP. 10/13/1988
315414 EP. 11/13/1988
8802253 WO. 09/13/1987
9101722 WO. 07/13/1990

International Class

A61K 009/16

Abstract

The present invention is directed to a diltiazem formulation suitable for one a day administration. The formulation contains a blend of diltiazem beads having two differing dissolution profiles.