U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Drug delivery apparatus and method

Patent 5286254 Issued on February 15, 1994. Estimated Expiration Date: Icon_subject August 28, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

578611

725731

873021

2123980

2499045

3542014

3865108

Dispensing instrument
Patent #: 4126134
Issued on: 11/21/1978
Inventor: Bolduc ,   et al.

Catheter apparatus with occlusion and flow diverting means
Patent #: 4137906
Issued on: 02/06/1979
Inventor: Akiyama ,   et al.

Catheter for the examination or treatment of a blood vessel and apparatus for the utilization of this catheter
Patent #: 4202346
Issued on: 05/13/1980
Inventor: Granier

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Inventors

Assignee

Application

No. 937464 filed on 08/28/1992

US Classes:

604/21, With tubular injection means inserted into body604/20, Infrared, visible light, ultraviolet, X-ray or electrical energy applied to body (e.g., iontophoresis, etc.)604/103.01, Delivering fluid or material through wall of inflated means604/913DILATORS MADE OF SWELLABLE MATERIAL [A61M 29/02]

Examiners

Primary: Rosenbaum, C. Fred
Assistant: Rafa, Michael

Attorney, Agent or Firm

Foreign Patent References

  • 299698 EP. 01/13/1989
  • 372088 EP. 06/13/1990
  • 147314 DE. 04/13/1981
  • 3915636 DE. 04/13/1990
  • 2582946 FR. 12/13/1986
  • 49-132888 JP. 12/13/1974
  • WO89/01794 WO. 03/13/1989
  • WO91/16945 WO. 11/13/1991
  • WO91/19529 WO. 12/13/1991
  • 588870 CH. 06/13/1977
  • 645273 CH. 09/13/1984
  • 1003853 SU 03/13/1983
  • 1069826 SU. 01/13/1984
  • 1069827 SU. 01/13/1984
  • 1146057 SU 03/13/1985
  • 1410973 SU. 07/13/1988

International Class

A61B 017/36

Abstract

A drug delivery apparatus and method for delivering a drug locally to internal body tissue. The invention contemplates positioning a drug delivery device in a body passageway or within body tissue and then selectively introducing a selected drug so that it is transported across a drug transport wall of the device for direct contact with the passageway wall or body tissue. A further aspect of the present invention involves treating a dilated vessel in the area of a stenotic lesion with a fixative or other drug to render the vessel biologically inert and to form a biological stent or prevent restenosis using specifically selected drugs. A still further aspect of the present invention involves treating a tumor or local or regional tissue mass with antitumor sensitizing agents, biological modifiers, antibiotics or other types of drugs by delivery of the drug to the tumor or tissue area directly or through the passageway wall.

Other References

  • Antich, Journal of Orthopaedic and Sports Physical Therapy, 4(2), 99-102 (1982)
  • Brand, Cardio, November, 48-56 (1989)
  • Ellman et al., Investigative Radiology, 19(5), 416-423 (1984)
  • Goldman et al., Atherosclerosis, 65, 215-225 (1987)
  • Jorgensen et al., The Lancet, May 20, 1106-1108 (1989)
  • Klimberg et al., Urology, 33(2), 153-158 (1989)
  • Layer et al., Br. J. Surg., 71, 709-710 (1984)
  • Okada et al., Stroke, 19(12), 1470-1476 (1988)
  • Okada et al., Neurosurgery, 25(6), 892-898 (1989)
  • Sheehan and Hrapchak, Theory and Practice of Histotechnology, Ch. 2, 40-50 1984)
  • Skauen et al., International Journal of Pharmaceutics, 20, 235-245 (1984)
  • Wolinsky et al., JAAC, 15(2),475-481 (1990)
  • BBI Newsletter, 13(5), 85-91 (1990
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