Patent ReferencesHydroxybenzylamino derivatives as anti-inflammatory agents Therapeutic method for treating radiation ulcers Treatment for inflammatory skin disease Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents Mature skin treatment and protectant compositions and methods of using same 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases Method of and composition for the prevention of solar radiation exposure-induced formation of carcinogenic skin lipid degradation products Device for stimulating salivation Patent #: 5078129 InventorApplicationNo. 887481 filed on 05/22/1992US Classes:604/20, Infrared, visible light, ultraviolet, X-ray or electrical energy applied to body (e.g., iontophoresis, etc.)128/898, Methods604/500MethodExaminersPrimary: Rosenbaum, C. FredAssistant: Rafa, Michael Attorney, Agent or FirmInternational ClassA61N 001/30AbstractA composition and method of applying a composition of (a) between about 10 and 15 percent vitamin C, plus or minus 10 percent, by weight to volume, (b) a viscosity agent, and (c) water as the remainder of the composition to healthy surface tissue overlying unhealthy tissue to be treated by radiation therapy for thereby abating dermatitis, mucositis, and esophagitis normally attendant with radiation therapy, the method comprising the steps of identifying the healthy surface tissue in the path of a radiation beam proposed to treat the unhealthy tissue, the identified healthy tissue being pretreated with vitamin C to increase the concentration of ascorbic acid in the identified healthy tissue; applying the composition to the identified healthy tissue; waiting a period of time of about at least one hour prior to radiation therapy so as to allow the vitamin C of the composition to increase the concentration of ascorbic acid in the healthy tissue whereby free radicals from ensuing radiation therapy are scavenged by the increased concentration of ascorbic acid in the healthy tissue; applying therapeutic radiation to the pretreated healthy tissue and the unhealthy tissue in a predetermined target dosage so that unhealthy tissue will be destroyed but so that the increased concentration of ascorbic acid in the healthy tissue will scavenge free radicals from the applied radiation; and scavenging free radicals from the applied radiation by the increased concentration of ascorbic acid in the healthy tissue so that dermatitis, mucositis, and esophagitis normally resulting from radiation therapy are abated. | |