Method for preparing samples for mass analysis by desorption from a frozen solution
Apparatus and method for laser desorption of molecules for quantitation
Instrument and method for the laser desorption of ions in mass spectrometry
Process and device for the laser desorption of an analyte molecular ions, especially of biomolecules
Laser ablation/ionizaton and mass spectrometric analysis of massive polymers
Method and apparatus for surface analysis Patent #: 5146088
ApplicationNo. 835970 filed on 02/20/1992
US Classes:250/288, With sample supply means250/282Methods
ExaminersPrimary: Dzierzynski, Paul M.
Assistant: Nguyen, Hiep T.
Attorney, Agent or Firm
Foreign Patent References
International ClassH01J 044/04
Foreign Application Priority Data1989-06-23 GB
AbstractA sample for analysis by Laser Desorption Mass Spectrometry is prepared by applying a substrate material to a target for the mass spectrometer, dissolving the sample material in a solvent and applying the solution to a substrate material on the target to be absorbed thereby. A matrix material is also dissolved in a solvent and this matrix material in solution is applied to the substrate material on the target. The solvent used to dissolve the matrix material is chosen such as to release the sample material from the substrate so that, after evaporation of the matrix material, there is provided on the substrate material an intimately mixed deposit of sample material and matrix material.