Compositions of digestive enzymes and salts of bile acids and process for preparation thereof
Patent 5260074 Issued on November 9, 1993. Estimated Expiration Date: 
June 22, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 22, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References Re30910 3004893 Stabilization and enhancement of enzymatic activity Preparation of enteric coated digestive enzyme compositions Process for the production of pancreatin pellets Enzyme-containing digestive aid compostions Cylindrical microtablets Dietary compositions and methods using bile salt-activated lipase Patent #: 4944944 InventorAssigneeApplicationNo. 901734 filed on 06/22/1992US Classes:424/497, Containing solid synthetic polymers424/94.1, ENZYME OR COENZYME CONTAINING424/94.2, Multienzyme complexes or mixtures of enzymes424/94.3, Stabilized enzymes or enzymes complexed with nonenzyme (e.g., liposomes, etc.)424/94.6, Hydrolases (3. ) (e.g., urease, lipase, asparaginase, muramidase, etc.)424/94.63, Acting on peptide bonds (3.4) (e.g., urokinease, etc.)435/213Trypsin; chymotrypsinExaminersPrimary: Robinson, Douglas W.Assistant: Larson, Kristin Foreign Patent References
International ClassesA61K 037/48A61K 037/62 A61K 009/16 C12N 009/76 AbstractDisclosed are gastric acid-resistant polymer-coated digestive enzymes/ursodeoxycholate compositions, process for their preparations and methods of treating digestive disorders, impaired liver function, cystic fibrosis, regulating the absorption of dietary cholesterol, and for dissolving gallstones by administering the compositions to a mammal in need of such treatment.Field of SearchMultienzyme complexes or mixtures of enzymesCoated (e.g., microcapsules) Containing solid synthetic polymers ENZYME OR COENZYME CONTAINING Stabilized enzymes or enzymes complexed with nonenzyme (e.g., liposomes, etc.) Hydrolases (3. ) (e.g., urease, lipase, asparaginase, muramidase, etc.) Acting on peptide bonds (3.4) (e.g., urokinease, etc.) Trypsin; chymotrypsin |
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