U.S. patents available from 1976 to present.
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Method of inducing lysine overproduction in plants

Patent 5258300 Issued on November 2, 1993. Estimated Expiration Date: Icon_subject November 2, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method for producing L-lysine by fermentation
Patent #: 4346170
Issued on: 08/24/1982
Inventor: Sano ,   et al.

Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use
Patent #: 4535060
Issued on: 08/13/1985
Inventor: Comai

Method for producing L-lysine by fermentation
Patent #: 4560654
Issued on: 12/24/1985
Inventor: Miwa ,   et al.

Tryptophan overproducer mutants of cereal crops
Patent #: 4642411
Issued on: 02/10/1987
Inventor: Hibberd ,   et al.

Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthase, production and use Patent #: 4769061
Issued on: 09/06/1988
Inventor: Comai

Inventors

Assignee

Application

No. 204388 filed on 06/09/1988

US Classes:

800/288, Nonplant protein is expressed from the polynucleotide435/414, Tobacco cell or cell line, per se435/418, Plant cell or cell line, per se, is pest or herbicide resistant or pest lethal435/419, Plant cell or cell line, per se, contains exogenous or foreign nucleic acid536/23.7, Encodes a microbial polypeptide800/292, Involving electroporation800/293, Involving particle-mediated transfecion (e.g., biolistic, etc.)800/294, Via Agrobacterium800/298, Higher plant, seedling, plant seed, or plant part (i.e., angiosperms or gymnosperms)800/317.3Tobacco

Examiners

Primary: Chereskin, Che S.

Attorney, Agent or Firm

Foreign Patent References

  • 0189707 EP. 06/13/1986
  • 0218571 EP 04/13/1987
  • 0271408 EP. 06/13/1988
  • 0240792 DE. 10/13/1987
  • WO8704181 WO. 07/13/1987

International Classes

A01H 004/00
C12N 015/32
C12N 005/14

Abstract

A method is provided for increasing the level of free L-lysine in a plant comprising: (a) introducing a foreign gene into the cells of a plant tissue source; and (b) expressing said foreign gene in said cells, wherein a first DNA sequence of said gene encodes dihydrodipicolinic acid synthase (DHDPS) which is substantially resistant to feedback inhibition by endogenously-produced free L-lysine.

Other References

  • Dauce-LeReverend, et al. (1982) European J. Appl. Microbiol. Biotechnol. 15:227-231
  • Richaud et al (1986) Journal of Bacteriology 166:297-300
  • Shan et al (Jul. 1986) Science 233:478-481
  • Vasil (Apr. 1988) Bio/Technology 6:397-402
  • Yugari et al., Biochem. Biophys. Acta, 62, 612 (1962
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