U.S. patents available from 1976 to present.
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[5(6)-(benzisoxa-,benzisothia-or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates

Patent 5256681 Issued on October 26, 1993. Estimated Expiration Date: Icon_subject August 27, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3657267

Inventors

Assignee

Application

No. 752521 filed on 08/27/1991

US Classes:

514/373, Polycyclo ring system having the thiazole ring as one of the cyclos514/379, Polycyclo ring system having the oxazole ring as one of the cyclos514/388, Nitrogen double bonded directly at 2-position of the diazole ring, or tautomeric equivalent548/212, Nitrogen attached directly to the thiazole ring by nonionic bonding548/241, Polycyclo ring system having the oxazole ring as one of the cyclos548/305.1The additional hetero ring is a cyclo in a polycyclo ring system (e.g., benzofuranyl-benzimidazole, etc.)

Examiners

Primary: Gerstl, Robert

Attorney, Agent or Firm

International Classes

C07D 413/04
C07D 403/04
C07D 417/04
A61K 031/415

Abstract

[5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1H-benzimidazol-2-yl]carbamates of formula (I) wherein R1 is hydrogen, C1-4 alkyl, halo, hydroxy or C1-4 alkyloxy; R2 is C1-4 alkyl; and X is O, S, SO, SO2 or NR3, said R3 being hydrogen, C1-4 alkyl, aryl or arylC1-4 alkyl. The compounds of formula (I) have anthelminthic properties. Compositions containing said compounds as active ingredient, a method of combating helminths, and a process for preparing said compounds and compositions.

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