U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Solid matrix system for transdermal drug delivery

Patent 5252334 Issued on October 12, 1993. Estimated Expiration Date: Icon_subject March 20, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3632740

3769071

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Use of eucalyptol for enhancing skin permeation of bio-affecting agents
Patent #: 4560553
Issued on: 12/24/1985
Inventor: Zupan

Bandage for sustained delivery of drugs
Patent #: 4655768
Issued on: 04/07/1987
Inventor: Marecki ,   et al.

Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration
Patent #: 4883669
Issued on: 11/28/1989
Inventor: Chien, et al.

Transdermal estrogen/progestin dosage unit, system and process
Patent #: 4906169
Issued on: 03/06/1990
Inventor: Chien, et al.

Percutaneous-administration-type pharmaceutical preparation of nitroglycerin
Patent #: 4971799
Issued on: 11/20/1990
Inventor: Nakagawa, et al.

Transdermal absorption dosage unit for postmenopausal syndrome treatment and process for administration Patent #: 5145682
Issued on: 09/08/1992
Inventor: Chien, et al.

Inventors

Assignee

Application

No. 857094 filed on 03/20/1992

US Classes:

424/448, Pressure sensitive adhesive means424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/449Transdermal or percutaneous

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

International Class

A61F 013/02

Abstract

A matrix for containing drugs for transdermal delivery systems is disclosed. The matrix, formed of a skin-adhesive acrylate copolymer, attains high rates of drug delivery without the addition of drug delivery rate enhancers. In preferred embodiments the matrix is used to administer steroids, in particular estradiol. Water-soluble polymers may be added as well.

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