Efficient microcapsule preparation and method of use
October 2, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3891570 Microencapsulation process Process for preparation of microspheres and modification of release rate of core material Method of preparing microspheres for intravascular delivery Microcapsule and micromatrix bodies and method for their formation Process for preparation of microspheres Polylactic acid microspheres and process for producing the same Polylactic acid type microspheres containing physiologically active substance and process for preparing the same Patent #: 5100669 InventorsAssigneeApplicationNo. 592020 filed on 10/02/1990US Classes:427/213.36, Solid-walled microcapsule formed from preformed synthetic polymer424/9.45, Halogenated benzene ring containing424/9.455, Carbonyl of a carboxylic acid or salt thereof attached directly to the benzene ring424/426, Errodable, resorbable, or dissolving424/497, Containing solid synthetic polymers427/213.3Solid encapsulation process utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)ExaminersPrimary: Stoll, Robert L.Assistant: Covert, John M. Attorney, Agent or FirmForeign Patent References
International ClassesB01J 013/12A61K 009/52 AbstractThe present invention relates to a method of preparing microcapsules suitable for encapsulation of therapeutic and diagnostic agents. The capsular coats are prepared from biodegradable polymers. In a particular aspect of the invention, surface charge of the polymeric material is altered by conjugation of an amino acid ester to the polymer, providing targeting to specific tissue cells. Encapsulation of hydrophilic radiodiagnostic agents in 1 μm capsules provides improved opacification. Encapsulation of cytotoxic agents in 100 μm capsules is useful in chemoembolization procedures.Other References
Field of SearchSolid encapsulation process utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)Solid-walled microcapsule formed from preformed synthetic polymer Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.) | |
