U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Compositions and methods for topical administration of pharmaceutically active agents

Patent 5234957 Issued on August 10, 1993. Estimated Expiration Date: Icon_subject December 23, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2142537

2277038

2352691

2501544

3249109

3632740

3640741

3814095

Dosage form
Patent #: 3972995
Issued on: 08/03/1976
Inventor: Tsuk ,   et al.

Therapeutically active, substituted piperidines and pyrrolidines therapeutic compositions thereof and methods of use thereof
Patent #: 4302465
Issued on: 11/24/1981
Inventor: AF Ekenstam ,   et al.

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Inventor

Assignee

Application

No. 813196 filed on 12/23/1991

US Classes:

514/772.6, Carboxylic acid containing monomer424/485, Natural gums, resin or latex424/486, Synthetic polymer424/487, Acrylic acid and derivatives424/488, Polysaccharides (e.g., cellulose, etc.)514/781, Cellulose or derivative514/782Natural gum or resin

Examiners

Primary: Page, Thurman K.
Assistant: Azpuru, Carlos

Attorney, Agent or Firm

Foreign Patent References

  • 0002425 EP. 06/13/1979
  • 0139127 EP. 05/13/1985
  • 0159168 EP. 10/13/1985
  • 250187 EP. 06/13/1987
  • 0331392 EP. 02/13/1989
  • 363224 EP. 10/13/1989
  • 217989A1 DE. 03/13/1983
  • 52460 LU. 11/13/1966
  • WO89/10740 WO. 11/13/1989
  • 352239 SE. 12/13/1972
  • 1360820 GB. 07/13/1974

International Class

A61K 047/32

Abstract

A composition for topical application comprising a therapeutically effective amount of a pharmaceutical agent(s), a flexible, finite, pharmaceutically acceptable, bioadhesive carrier, and a solvent for the pharmaceutical agent(s) in the carrier and a method of administering the pharmaceutical agent to a mammal are disclosed.

Other References

  • "Molecular Mechanisms of Local Anesthesia: A Review", by John F. Butterworth, Garry R. Strichartz. Anesthesiology 72:711-754, 1990. Pertinent pp. 720-72
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