Compositions of gastric acid-resistant microspheres containing salts of bile acids
Patent 5234697 Issued on August 10, 1993. Estimated Expiration Date: 
June 22, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 22, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References Re30910 3004893 Preparation of enteric coated digestive enzyme compositions Process for the production of pancreatin pellets Bile acid derivatives and production thereof Cylindrical microtablets Ursodeoxycholic acid derivatives and their inorganic and organic salts having therapeutic activity, and process for preparing the same Patent #: 4865765 InventorAssigneeApplicationNo. 902578 filed on 06/22/1992US Classes:424/490, Coated (e.g., microcapsules)424/489Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)ExaminersPrimary: Page, Thurman K.Assistant: Benston, William E. Jr. Foreign Patent References
International ClassA61K 009/16AbstractDisclosed are gastric acid-resistant polymer-coated ursodeoxycholate compositions, process for their preparations and-methods of treating digestive disorders, impaired liver function, autoimmune diseases of the liver and biliary tract, prevention of colon cancer following cholecystectomy, cystic fibrosis, dissolving gallstones and regulating dietary cholesterol absorption by administering said compositions to a mammal in need of such treatment.Field of SearchCoated (e.g., microcapsules)Particulate form (e.g., powders, granules, beads, microcapsules, and pellets) Oxygen bonded directly at the 6- or 7-position (e.g., chenodeoxycholic acids, ursodeoxycholic acids, etc.) Oxygen single bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system | |
