U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents

Patent 5231188 Issued on July 27, 1993. Estimated Expiration Date: Icon_subject May 13, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Re29607

5-Halomethyl-3-phenyl-2-oxazolidinones
Patent #: 4128654
Issued on: 12/05/1978
Inventor: Fugitt ,   et al.

Novel 5-hydroxymethyl oxazolidinones, the method of preparing them and their application in therapeutics
Patent #: 4250318
Issued on: 02/10/1981
Inventor: Dostert ,   et al.

3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
Patent #: 4340606
Issued on: 07/20/1982
Inventor: Fugitt ,   et al.

P-Oxooxazolidinylbenzene compounds as antibacterial agents
Patent #: 4461773
Issued on: 07/24/1984
Inventor: Gregory

Aminomethyl-5 oxazolidinic derivatives and therapeutic use thereof
Patent #: 4476136
Issued on: 10/09/1984
Inventor: Dostert ,   et al.

Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
Patent #: 4705799
Issued on: 11/10/1987
Inventor: Gregory

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
Patent #: 4801600
Issued on: 01/31/1989
Inventor: Wang ,   et al.

Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents Patent #: 4921869
Issued on: 05/01/1990
Inventor: Wang, et al.

Inventor

Assignee

Application

No. 882407 filed on 05/13/1992

US Classes:

548/221, Chalcogen bonded directly at the 2-position of the oxazole ring544/137, The five-membered hetero ring has at least oxygen and nitrogen as ring hetero atoms546/271.7Polycyclo ring system having the 1,3-oxazole ring as one of the cyclos

Examiners

Primary: Ivy, C. Warren
Assistant: Spivack, Phyllis G.

Attorney, Agent or Firm

Foreign Patent References

  • 127902 EP. 12/13/1984
  • 184170 EP. 06/13/1986
  • 312000 EP. 04/13/1989
  • 316594 EP. 05/13/1989
  • 352781 EP. 01/13/1990
  • 322263 FR. 06/13/1989
  • WO90/02744 WO. 03/13/1990

International Class

C07D 263/52

Abstract

The present invention involves tricyclic-fused 6-member ring oxazolidinones ##STR1## and tricyclic-fused 5-member ring oxazolidinones ##STR2## which are useful as antibacterial agents.

Other References

  • Slee, A. M., et al., Antimicrobial Agents and Chemotherapy, 31, pp. 1791-1797 (1987)
  • Gregory, Walter A., et al., J. Med. Chem., 32, pp. 1673-1681 (1989)
  • Wang, Chia-Lin, et al., Tetrahedron, 45, pp. 1323-1326 (1989
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