Delivery system comprising means for controlling internal pressure

Patent 5229133 Issued on July 20, 1993. Estimated Expiration Date:

March 12, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventors

Assignee

ALZA Corporation

Application

No. 850087 filed on 03/12/1992

US Classes:

424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/438, Specially adapted for ruminant animal604/892.1Osmotic or diffusion pumped device or system

Examiners

Primary: Page, Thurman K.
Assistant: Phelan, D. Gabrielle

Attorney, Agent or Firm

Larson; Jacqueline S., Sabatine; Paul L., Stone; Steven F.

Foreign Patent References

031043 EP. 06/13/1989

International Class

A61K 009/24

Abstract

A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a semipermeable housing defining a internal space, (2) an optional and presently preferred in the space, (3) a heat responsive composition comprising a beneficial agent in the space, (4) a space consuming member in the device, (5) a non-toxic compound blended with the heat responsive composition for enhancing its viscosity; (6) an exit port in the wall for increasing the internal pressure of the dispenser and for simultaneously letting the beneficial agent exit through said port from the device, and (7) an embodiment comprising a prehydrating fluid for fastening the start-up of delivery from the delivery system.