Biodegradable magnetic microcluster comprising non-magnetic metal or metal oxide particles coated with a functionalized polymer
Patent 5225282 Issued on July 6, 1993. Estimated Expiration Date: 
December 13, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 13, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethod of magnetic resonance imaging of the liver and spleen Method for enhancing NMR imaging; and diagnostic use Magnetic powder composition Patent #: 4820338 InventorsApplicationNo. 806478 filed on 12/13/1991US Classes:428/407, Including synthetic resin or polymer252/62.54, Synthetic resin252/62.58, With boron, aluminum, thallium, or indium252/62.64, Magnesium424/9.322, Polymer containing (e.g., polypeptide, synthetic resin, etc.)436/173, NUCLEAR MAGNETIC RESONANCE, ELECTRON SPIN RESONANCE OR OTHER SPIN EFFECTS OR MASS SPECTROMETRY436/526MagneticExaminersPrimary: Thibodeau, Paul J.Assistant: Resan, Stevan A. Attorney, Agent or FirmForeign Patent References
International ClassB32B 027/00AbstractSubdomain metal or metal oxide particles covalently coupled to chemically reactive organic moieties and subsequently reacted together to form biodegradable magnetic microclusters are disclosed. The magnetic microcluster can be used as contrast agents in NMR imaging for the production of images suitable for use in diagnosis, for in vivo delivery and targeting of drugs, as in vivo, biodegradable agents for the sequestering of free metal ions in the treatment of metal driven disease. |
| ||||||||||||||
