Pharmaceutical formulation
Patent 5225197 Issued on July 6, 1993. Estimated Expiration Date: 
July 6, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 6, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3039922 Effervescent tablet and method Chewing gum containing a medicament and taste maskers Effervescent antacid and analgesic compositions Therapeutic compositions Disintegrating tablet and process for its preparation Chewable medicament tablet containing means for taste masking Patent #: 4851226 InventorsAssigneeApplicationNo. 515200 filed on 04/27/1990US Classes:424/440, Candy, candy coated or chewing gum424/466, Effervescent424/468, Sustained or differential release type424/470Where particles are granulatedExaminersPrimary: Page, Thurman K.Assistant: Benston, William E. Jr. Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/68Foreign Application Priority Data1989-04-28 GBAbstractA chewable tablet comprises a medicament dispersed in a chewable base, such as mannitol, together with an effervescent couple, such as citric acid - sodium bicarbonate. The combination of effervescence and chewability with optional flavorings improves the taste characteristics of the medicament in oral adminstration. A disintegrant such as microcrystalline cellulose may be added to give the patient the option of dispersing the tablet in water.Other References
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