U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Transdermal estradiol delivery system

Patent 5223261 Issued on June 29, 1993. Estimated Expiration Date: Icon_subject December 31, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3598122

3598123

Dosage for coadministering drug and percutaneous absorption enhancer
Patent #: 4379454
Issued on: 04/12/1983
Inventor: Campbell ,   et al.

Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer
Patent #: 4460372
Issued on: 07/17/1984
Inventor: Campbell ,   et al.

Process for obtaining composite pharmaceutical preparation
Patent #: 4485087
Issued on: 11/27/1984
Inventor: Otsuka ,   et al.

Device for the administration of an active agent to the skin or mucosa
Patent #: 4573996
Issued on: 03/04/1986
Inventor: Kwiatek ,   et al.

Transdermal systemic dosage forms
Patent #: 4585452
Issued on: 04/29/1986
Inventor: Sablotsky

Transdermal administration of fentanyl and device therefor
Patent #: 4588580
Issued on: 05/13/1986
Inventor: Gale ,   et al.

Method of transdermal drug delivery
Patent #: 4624665
Issued on: 11/25/1986
Inventor: Nuwayser

Patch
Patent #: 4685911
Issued on: 08/11/1987
Inventor: Konno ,   et al.

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Inventors

Assignee

Application

No. 815908 filed on 12/31/1991

US Classes:

424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/447, Bandages with incorporated medicaments424/448, Pressure sensitive adhesive means424/449Transdermal or percutaneous

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

Foreign Patent References

  • 0062682 EP. 10/13/1982
  • 0156080 EP. 10/13/1985
  • 0272987 EP. 06/13/1988
  • 0279986 EP. 08/13/1988
  • 57-075917 JP. 05/13/1982
  • 1518683 GB. 07/13/1978
  • 2086224 GB. 05/13/1982
  • 2158355 GB. 12/13/1985

International Class

A61F 013/00

Abstract

A pressure-sensitive adhesive sheet material for delivering estradiol to skin, the sheet material comprising a backing with a layer of a pressure-sensitive adhesive adjacent thereto, said pressure-sensitive adhesive layer comprising a pressure-sensitive adhesive polymer, two or more skin penetration-enhancing ingredients and estradiol. The sheet material is useful for systemic treatment of conditions associated with estradiol deficiency. Methods of using such adhesive sheet material are also described.

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