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Formulations for stabilizing fibroblast growth factor

Patent 5217954 Issued on June 8, 1993. Estimated Expiration Date: Icon_subject June 8, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Isolation of fibroblast growth factor
Patent #: 4785079
Issued on: 11/15/1988
Inventor: Gospodarowicz ,   et al.

Preparation which promotes the absorption of peptides
Patent #: 4900730
Issued on: 02/13/1990
Inventor: Miyauchi

Isolation of fibroblast growth factor Patent #: 4902782
Issued on: 02/20/1990
Inventor: Gospodarowicz, et al.

Inventors

Assignee

Application

No. 504340 filed on 04/04/1990

US Classes:

514/12, 25 or more peptide repeating units in known peptide chain structure514/21, Produced by or extracted from animal tissue514/970, CONTAINING DESIGNATED INGREDIENT TO STABILIZE AN ACTIVE INGREDIENT530/399Hormones, e.g., prolactin, thymosin, growth factors, etc.

Examiners

Primary: Moezie, F. T.

Attorney, Agent or Firm

International Class

A61K 037/36

Abstract

Pharmaceutical formulations and a method for their preparation are provided. These formulations provide a stabilized basic fibroblast growth factor (bFGF) which is less susceptible to oxidation or metal-induced aggregation by including an amount of a chelating agent effective to stabilize the bFGF.

Other References

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