Antibacterial coated medical implants
March 11, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesIonogenic hydrophilic water-insoluble gels from partially hydrolyzed acrylonitrile polymers and copolymers, and a method of manufacturing same Thermoplastic polyurethane anticoagulant alloy coating Antibiotic bonded prosthesis and process for producing same Antimicrobial coated implants Drug bonded prosthesis and process for producing same Coating medical devices with cationic antibiotics Antimicrobial wound dressing and skin fixator for percutaneous conduits Antimicrobial device and method Method of making antimicrobial coated implants Anti-infective and antithrombogenic medical articles and method for their preparation Patent #: 5013306 InventorsAssigneeApplicationNo. 850197 filed on 03/11/1992US Classes:623/11.11, IMPLANTABLE PROSTHESIS604/265With body soluble, antibactericidal or lubricating materials on conduitExaminersPrimary: Isabella, David J.Attorney, Agent or FirmInternational ClassA61F 002/02AbstractAn implantable medical device having long lasting resistance to staphylococcal biofilm colonization is provided. Implantable medical devices such as catheters, shunts, prosthesis, pacemakers, etc. are susceptible to colonization by biofilm adherent microorganisms, especially staphylococci. While systemic staphylococcal infections are effectively treated by many antibiotics, vancomycin being the antibiotic of choice, this same bacteria when encased in biofilm adhering to indwelling medical devices is generally resistant to antibiotic treatment. By the present invention, the combination of rifampin and minocycline or the combination of rifampin and novobiocin when coated on the surfaces of implantable medical devices unexpectedly provides superior antibacterial activity against staphylococcal biofilm colonization on the coated surface of indwelling medical devices.Other References
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