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Catechol derivatives, and preventive and remedial preparations for regressive disorders in the central nervous system containing the same

Patent 5214034 Issued on May 25, 1993. Estimated Expiration Date: Icon_subject December 3, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Non-steroidal anti-inflammatory compounds to treat inflammation
Patent #: 4559328
Issued on: 12/17/1985
Inventor: Smerbeck ,   et al.

Catecholamine derivatives, a process for their preparation and pharmaceutical compositions thereof Patent #: 4608391
Issued on: 08/26/1986
Inventor: Ginos ,   et al.

Inventors

Assignee

Application

No. 801866 filed on 12/03/1991

US Classes:

514/159, Ortho-hydroxybenzoic acid (i.e., salicyclic acid) or derivative DOAI514/533Compound contains two or more C(=O)O groups indirectly bonded together by only conalent bonds

Examiners

Primary: Waddell, Frederick E.
Assistant: Weddington, Kevin E.

Attorney, Agent or Firm

Foreign Patent References

  • 0185522 EP. 06/21/1986
  • 916208 DE. 08/21/2013
  • 2155985 DE. 05/21/1973
  • 1256914 GB. 12/21/1971

International Classes

A61K 031/60
A61K 031/235

Foreign Application Priority Data

1986-09-26 JP

Abstract

Catechol derivatives which relate to the production of nerve growth factor in particular tissues of brain are disclosed.Methods for the synthesis, data on the physiological activity, and data on the toxicity of these derivatives as well as examples of preparation for their administration are also disclosed.The disclosed derivatives provide preventive and remedial effect for regressive disorders in the central nervous system including senile dementia of Alzheimer type.

Other References

  • Chemical Abstracts (104:219729u) 1986
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