Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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AbstractAn article for controlled delivery of an active substance into an aqueous phase has a first layer containing an active substance, and a second layer of a crystalline polymer matrix and a non-ionic surface active agent, the second layer also containing the same or different active substance substantially homogeneously dispersed therein. The article enables release of a drug at a constant plateau level, followed by a pulse of drug after a predetermined time, thus making the composition of the invention especially suitable for use in, e.g., treatment of rheumatoid arthritis or related disorders with non-steroidal anti-inflammatory agents. | InventorsAssigneeApplicationNo. 505924 filed on 04/06/1990US Classes:424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/485, Natural gums, resin or latex424/488Polysaccharides (e.g., cellulose, etc.)Field of Search424/485, Natural gums, resin or latex424/488, Polysaccharides (e.g., cellulose, etc.)424/473With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)ExaminersPrimary: Page, Thurman K.Assistant: Phelan, D. Gabrielle Attorney, Agent or FirmUS Patent References3634584, 4177256, Osmotic bursting drug delivery deviceIssued on: 12/04/1979 Inventor: Michaels , et al.4182330, Means for administering amphipathic medicament Issued on: 01/08/1980 Inventor: Michaels4343789, Sustained release pharmaceutical composition of solid medical material Issued on: 08/10/1982 Inventor: Kawata , et al.4359483, Process for producing a multi-layered slow release composite Issued on: 11/16/1982 Inventor: Kaetsu , et al.4486471, Process for preparing ethylcellulose microcapsules Issued on: 12/04/1984 Inventor: Samejima , et al.4576604, Osmotic system with instant drug availability Issued on: 03/18/1986 Inventor: Guittard , et al.4629261, Centering and safety device for rotors supported without contact Issued on: 12/16/1986 Inventor: Eiermann , et al.4673405, Osmotic system with instant drug availability Issued on: 06/16/1987 Inventor: Guittard , et al.4723958, Pulsatile drug delivery system Issued on: 02/09/1988 Inventor: Pope , et al.4744074, Disk-type recording medium Issued on: 05/10/1988 Inventor: Imanaka , et al.4744976, Erodible matrix for sustained release bioactive composition Issued on: 05/17/1988 Inventor: Snipes , et al.4806337, Erodible matrix for sustained release bioactive composition Issued on: 02/21/1989 Inventor: Snipes , et al.4810502, Pseudoephedrine brompheniramine therapy Issued on: 03/07/1989 Inventor: Ayer , et al.5023088Multi-unit delivery system Issued on: 06/11/1991 Inventor: Wong, et al. Foreign Patent References
International ClassA61K 009/24Foreign Application Priority Data1989-09-22 DK |