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Patent No. 5970981

Mouthguard made at least partially from an edible candy

A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.

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US Patent 5213808 - Controlled release article with pulsatile release

US Patent Issued on May 25, 1993
Estimated Patent Expiration Date: Icon_subject May 25, 2010Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

An article for controlled delivery of an active substance into an aqueous phase has a first layer containing an active substance, and a second layer of a crystalline polymer matrix and a non-ionic surface active agent, the second layer also containing the same or different active substance substantially homogeneously dispersed therein. The article enables release of a drug at a constant plateau level, followed by a pulse of drug after a predetermined time, thus making the composition of the invention especially suitable for use in, e.g., treatment of rheumatoid arthritis or related disorders with non-steroidal anti-inflammatory agents.

Inventors

Assignee

Application

No. 505924 filed on 04/06/1990

US Classes:

424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/485, Natural gums, resin or latex424/488Polysaccharides (e.g., cellulose, etc.)

Field of Search

424/485, Natural gums, resin or latex424/488, Polysaccharides (e.g., cellulose, etc.)424/473With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)

Examiners

Primary: Page, Thurman K.
Assistant: Phelan, D. Gabrielle

Attorney, Agent or Firm

US Patent References

3634584, 4177256, Osmotic bursting drug delivery device
Issued on: 12/04/1979
Inventor: Michaels ,   et al.
4182330, Means for administering amphipathic medicament
Issued on: 01/08/1980
Inventor: Michaels
4343789, Sustained release pharmaceutical composition of solid medical material
Issued on: 08/10/1982
Inventor: Kawata ,   et al.
4359483, Process for producing a multi-layered slow release composite
Issued on: 11/16/1982
Inventor: Kaetsu ,   et al.
4486471, Process for preparing ethylcellulose microcapsules
Issued on: 12/04/1984
Inventor: Samejima ,   et al.
4576604, Osmotic system with instant drug availability
Issued on: 03/18/1986
Inventor: Guittard ,   et al.
4629261, Centering and safety device for rotors supported without contact
Issued on: 12/16/1986
Inventor: Eiermann ,   et al.
4673405, Osmotic system with instant drug availability
Issued on: 06/16/1987
Inventor: Guittard ,   et al.
4723958, Pulsatile drug delivery system
Issued on: 02/09/1988
Inventor: Pope ,   et al.
4744074, Disk-type recording medium
Issued on: 05/10/1988
Inventor: Imanaka ,   et al.
4744976, Erodible matrix for sustained release bioactive composition
Issued on: 05/17/1988
Inventor: Snipes ,   et al.
4806337, Erodible matrix for sustained release bioactive composition
Issued on: 02/21/1989
Inventor: Snipes ,   et al.
4810502, Pseudoephedrine brompheniramine therapy
Issued on: 03/07/1989
Inventor: Ayer ,   et al.
5023088Multi-unit delivery system
Issued on: 06/11/1991
Inventor: Wong, et al.

Foreign Patent References

  • 103387 EP. 08/13/1983
  • 117164 EP. 01/13/1984
  • 132384 EP. 07/13/1984
  • 199362 EP. 04/13/1986
  • 230654 EP. 12/13/1986
  • 232877 EP. 02/13/1987
  • 1-10622 JP. 04/13/1989
  • 2160100 GB. 06/13/1985
  • 2189995 GB. 04/13/1987
  • WO8904673 WO. 06/13/1989

International Class

A61K 009/24

Foreign Application Priority Data

1989-09-22 DK

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