U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method of determining a site of inflammation utilizing ELAM-1 ligands

Patent 5211937 Issued on May 18, 1993. Estimated Expiration Date: Icon_subject April 11, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Article and method for measuring glucose level in body fluids Patent #: 4330299
Issued on: 05/18/1982
Inventor: Cerami

Inventors

Assignee

Application

No. 683458 filed on 04/11/1991

US Classes:

424/1.73, Attached to carbohydrate compound; derivative thereof (e.g., DNA, nucleotide, nucleoside, sugar, starch, tannin, saccharide, polysaccharide, cellulose, O-, N- and S-glycoside, vitamin B12)424/1.21Molecular bilayer structure (e.g., vesicle, liposome)

Examiners

Primary: Maples, John S.

Attorney, Agent or Firm

Foreign Patent References

  • 0319253 EP. 06/13/1989
  • 9013300 WO. 11/13/1990
  • 9119501 WO. 12/13/1991
  • 9119502 WO. 12/13/1991

International Classes

A61K 049/02
A61K 049/00

Abstract

Ligands in the form of N-acetyllactosamines which bind to endothelial leukocyte adhesion molecule-1 (ELAM-1) are disclosed. The ligand compounds can be formulated into pharmaceutical compositions and/or assay compositions used to alleviate inflammation and assay for the presence of (qualitative) and amount of (quantitative) ELAM-1 and thereby determine the presence, location and degree of inflammation.

Other References

  • European Search Report
  • Lamblin et al., Journal of Biological Chemistry (1984) 259(14):9051-9058
  • Stanley et al., Journal of Biological Chemistry (1988) 263(23):11374-11381
  • Michalski et al., FEBS Letters (1977) 79(1):101-104
  • Lowe et al., Cell (1990) 63:475-484
  • Brandley et al., Cell (1990) 63:861-863
  • Gnewuch et al., Chem. Rev. (1986) 86:203-23
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?