Ultrasonic treatment of pathological tissue

Patent 5209221 Issued on May 11, 1993. Estimated Expiration Date:

September 20, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

3237623

3499437

3526219

3589363

3735755

High frequency ultrasonic process and apparatus for selectively dissolving and removing unwanted solid and semi-solid materials and the like
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Issued on: 03/02/1976
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Patent #: 4315514
Issued on: 02/16/1982
Inventor: Drewes , et al.

Acoustic diode
Patent #: 4618796
Issued on: 10/21/1986
Inventor: Riedlinger

Ultrasound hyperthermia applicator with variable coherence by multi-spiral focusing
Patent #: 4622972
Issued on: 11/18/1986
Inventor: Giebeler, Jr.

Apparatus for producing time-staggered shock waves
Patent #: 4664111
Issued on: 05/12/1987
Inventor: Reichenberger

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Inventor

Riedlinger, Rainer

Assignee

Richard Wolf GmbH

Application

No. 763475 filed on 09/20/1991

US Classes:

601/2, Ultrasonic601/4Contact-free comminution of concretion

Examiners

Primary: Cohen, Lee S.
Assistant: Pontius, Kevin

Attorney, Agent or Firm

Panitch Schwarze Jacobs & Nadel

Foreign Patent References

3300121 DE. 07/13/1983
3331510 DE. 03/13/1984
3527586 DE. 12/13/1986
2113099 GB. 08/13/1983
2176110 GB. 12/13/1986

International Class

A61H 023/00

Foreign Application Priority Data

1988-03-01 DE

Abstract

A device for generating sonic signal forms for limiting, preventing or regressing the growth of pathological tissue comprises an ultrasonic transmission system for transmitting sound waves, focussed on the tissue to be treated, by way of a coupling medium. An ultrasonic signal produced at the focus of the system comprises brief pulses having at least one rarefaction phase with a negative sonic pressure amplitude with a value greater than 2×105 Pa. The ultrasonic signal is radiated with a carrier frequency exceeding 20 kHz, a sonic pulse duration T of less than 100 μs and a pulse recurrence rate of less than 1/(5T). The device produces controlled cavitation in the tissue to be treated.

Other References

F. J. Fry, "Precision High Intensity Focusing Ultrasonic Machines for Surgery," Am. J. Physical Med., vol. 37, No. 3, p. 152 (Jun. 1958)
L. D. Rosenberg, "La Generation et l'Etude des Vibrations Ultra-Sonores de Tres Grande Intensite," Acustica, vol. 12, p. 40 (1962)
P. P. Lele, "Production of Deep Focal Lesions by Focused Ultrasound--Current Status," Ultrasonics, Apr. 1967, p. 105
L. R. Gavrilov, N. P. Narbut and F. E. Fridman, "Use of focused ultrasound to accelerate the `maturing` of a cataract," Sov. Phys. Acoust., vol. 20, No. 3, p. 229 (Nov.-Dec. 1974)
D. J. Coleman, F. L. Lizzi, and F. A. Jakobiec, "Therapeutic Ultrasound in the Production of Ocular Lesions," Am. J. Ophth., 86:185, 1978
D. J. Coleman, F. L. Lizzi, A. A. M. El-Mofty, J. Driller, and L. A. Franzen, "Ultrasonically Accelerated Resorption of Vitreous Membranes," Am. J. Ophth., 89:490 1980
D. J. Coleman, F. L. Lizzi, S. Chang, and J. Driller, "Applications of Therapeutic Ultrasound in Ophthalmology," Prog. in Med. Ultrasound, vol. 2, 1981, p. 263
F. L. Lizzi, J. Driller, and M. Ostromogilsky, "Thermal Model for Ultrasonic Treatment of Glaucoma," Ultrasound in Med. & Biol., vol. 10, No. 3, p. 289 (1984)
Brendel et al., "Effect of Shock Waves on the Microvasculature", Prog. Appl. Microcirc., vol. 12, pp. 41-50 (1987)
Wilmer et al., "Effeckt von Stosswellen auf Tomorzellen in Suspension," 64th Convention, Union of Baravian Surgeons (Jul. 1987)
Eugen Skudrzyk, The Foundations of Acoustics, pp. 295-296, Springer-Verlag, Wien-New York (1971)
Heinrich Kuttruff, Room Acoustics, p. 22, Applied Science Publishers Ltd., London (1973