Transmucosal formulations of low molecular weight peptide drugs
Patent 5204108 Issued on April 20, 1993. Estimated Expiration Date: 
April 20, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 20, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethod and preparation for administration to the mucosa of the oral or nasal cavity Powdery pharmaceutical composition for nasal administration Piptides having ANF activity Patent #: 4816443 InventorAssigneeApplicationNo. 469443 filed on 04/09/1990US Classes:424/434, Mucosal (e.g., nasal, etc.)424/435, Mouth424/436, Anal, rectal (e.g., suppositories, etc.)424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/491, Containing proteins and derivatives424/492, Gelatin424/494, Cellulose derivatives514/718Plural oxygensExaminersPrimary: Page, Thurman K.Assistant: Azpuru, Carlos Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/14A61K 009/16 A61K 009/50 A61K 031/075 Foreign Application Priority Data1987-10-10 GBAbstractA drug delivery composition comprising a plurality of microspheres and active drug associated with each microsphere, the drug being for systemic delivery and having a maximum molecular weight of 6000, and the composition being substantially free of an enhancer. The microspheres may be of starch, gelatin or albumin. Suitable drugs include peptides, such as insulin, and antigenic vaccine ingredients. The compositions are suitable for delivery across a mucosal surface such as the vagina, eye or nose.Other References
Field of SearchMouthAnal, rectal (e.g., suppositories, etc.) Mucosal (e.g., nasal, etc.) Particulate form (e.g., powders, granules, beads, microcapsules, and pellets) Coated (e.g., microcapsules) Containing proteins and derivatives Gelatin Cellulose derivatives Nitrates or nitrites or nitric acid or nitrogen oxides | |
