Pharmaceutical sustained release matrix and process
October 22, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3121044 3773921 Slow release pharmaceutical compositions New oral form of medicament and a method for producing it Pharmaceutical compositions Pharmaceutical formulation for slow release via controlled surface erosion Controlled release formulations of orally-active medicaments Directly compressible acetaminophen granulation Sustained release tablet containing at least 95 percent theophylline Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate InventorsApplicationNo. 600279 filed on 10/22/1990US Classes:424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/470, Where particles are granulated424/472Layered unitary dosage formsExaminersPrimary: Page, Thurman K.Assistant: Horne, Leon R. Foreign Patent References
International ClassA61R 009/72AbstractA pharmaceutical sustained release homogeneous tablet or homogeneous tablet layer is formed by making a wet granulation using povidone (PVP) in alcohol as the granulating fluid which is mixed with a pharmaceutical active, ethylcellulose, a wicking agent, e.g. microcrystalline cellulose, an erosion promoter, e.g. pregelatinized starch, then drying and milling the granulation and blending with a dry powdered erosion promotor, wicking agent, lubricant, e.g. magnesium stearate and glidant, e.g. silicon dioxide, and compressing the resultant granulation, which upon administration results in a long-lasting slow and relatively regular incremental release of the pharmaceutical active, and multi-layered pharmaceutical active tablets comprising immediate release and/or sustained release layers.Other References
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