U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Drug delivery collagen-impregnated synthetic vascular graft

Patent 5197977 Issued on March 30, 1993. Estimated Expiration Date: Icon_subject April 30, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3272204

3425418

3928653

Double-velour synthetic vascular graft
Patent #: 4047252
Issued on: 09/13/1977
Inventor: Liebig ,   et al.

Blood vessel prosthesis
Patent #: 4416028
Issued on: 11/22/1983
Inventor: Eriksson ,   et al.

Method for forming impregnated synthetic vascular grafts Patent #: 4842575
Issued on: 06/27/1989
Inventor: Hoffman, Jr. ,   et al.

Inventors

Assignee

Application

No. 877344 filed on 04/30/1992

US Classes:

623/1.45, Impregnation427/2.25, Liquid conveying (e.g., vascular, arterial, bile duct, urethra)623/1.39, Having pores623/1.42, Drug delivery623/1.47, Collagen623/1.5, Knitted623/1.52Velour surface

Examiners

Primary: Isabella, David J.

Attorney, Agent or Firm

Foreign Patent References

  • 0000949 EP 03/13/1979
  • 2601289 DE 07/13/1977
  • 0904693 SU 02/13/1982

International Class

B61F 002/06

Abstract

A collagen impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linking the collagen in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, antifungal agents and the like.

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