U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method of controlling drug release by resonant sound wave

Patent 5190766 Issued on March 2, 1993. Estimated Expiration Date: Icon_subject April 12, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method for comminuting kidney stones
Patent #: 4825851
Issued on: 05/02/1989
Inventor: Cocks ,   et al.

Method for comminuting kidney stones Patent #: 4892089
Issued on: 01/09/1990
Inventor: Cocks, et al.

Inventor

Application

No. 684386 filed on 04/12/1991

US Classes:

424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/491, Containing proteins and derivatives424/493, Containing polysaccharides (e.g., sugars)424/499, Contains proteins or derivative or polysaccharides or derivative604/22With means for cutting, scarifying, or vibrating (e.g., ultrasonic, etc.) tissue

Examiners

Primary: Page, Thurman K.
Assistant: Hulina, Amy

Attorney, Agent or Firm

International Class

A61K 009/52

Foreign Application Priority Data

1990-04-16 JP

Abstract

A drug carrier carrying a drug is introduced to a diseased region of the living body while it is observed in the B mode echograms. The drug carrier is irradiated with an ultrasonic wave for strongly vibrating the drug carrier, thereby releasing the drug from the drug carrier for curing the diseased portion.

Other References

  • "Microcapsule Drug Delivery System as Micromachine Using Resonant Ultrasound", Japan Soc. ME and BE p. 49 (Oct. 1989)
  • "Localization of Sonodynamic Effect for Cancer Treatment: Study of Acoustic Chemical Therapy (II)" Proceedings of the 55th Meeting of Japan Society of Ultrasonics in Medicine, pp. 683-684 (1989)
  • "Combination Treatment of Ultrasound and Drug on Tumor", Proceedings of the 54th Meeting of the Japan Society of Ultrasonics in Medicine, pp. 257 to 258 (1989)
  • "Ultrasonic Control of Drug Releasing", Japan J. Artificial Organs, vol. 13, No. 3, pp. 1205 to 1208 (1989)
  • Ken Ishihara et al., "New Approach to Noninvasive Manometry Based on Pressure Dependent Resonant Shift of Elastic Microcapsules in Ultrasonic Frequency Characteristics", Japanese Journal of Applied Physics, vol. 27 (1988), Supplement 27-1, pp. 125-12
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