U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Solid pharmaceutical composition

Patent 5190760 Issued on March 2, 1993. Estimated Expiration Date: Icon_subject May 21, 2012. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3773921

Rumen-stable pellets
Patent #: 4181708
Issued on: 01/01/1980
Inventor: Dannelly

Method for establishing blood levels of biocide in animals
Patent #: 4612186
Issued on: 09/16/1986
Inventor: Eckenhoff ,   et al.

Programmed release device and method of use thereof
Patent #: 4643893
Issued on: 02/17/1987
Inventor: Ascher ,   et al.

Medication and method for treating heartworms in dogs
Patent #: 4789548
Issued on: 12/06/1988
Inventor: Tisdale

Tablet for pharmaceutical use able to release active substances at successive times
Patent #: 4865849
Issued on: 09/12/1989
Inventor: Conte ,   et al.

Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked Patent #: 5082669
Issued on: 01/21/1992
Inventor: Shirai, et al.

Inventor

Assignee

Application

No. 887393 filed on 05/21/1992

US Classes:

424/438, Specially adapted for ruminant animal424/472, Layered unitary dosage forms424/480, Cellulose or derivative424/482Containing solid synthetic polymers

Examiners

Primary: Page, Thurman K.
Assistant: Phelan, D. Gabrielle

Attorney, Agent or Firm

Foreign Patent References

  • 838506 BE. 02/13/1976
  • 0236002 EP. 02/13/1987
  • 0238207 EP. 09/13/1987
  • 1330829 GB. 09/13/1973
  • 1499672 GB. 02/13/1978

International Class

A23K 001/18

Foreign Application Priority Data

1989-07-08 GB

Abstract

A solid pharmaceutical composition for release of a biologically active substance into a desired aqueous environment, containing a core and an outer layer, said core comprising between 17 and 93% by weight of the biologically active substance, between 0.01 and 7% by weight of a water swellable polymer material and between 0 and 83% of one or more accessory ingredients, relative to the total weight of the core; and the outer layer comprising between 25 and 75% by weight of the biologically active substance, between 25 and 75% by weight of a material for enabling rapid dispersion of the outer layer into the aqueous environment and 0 to 50% by weight of one or more accessory ingredients, relative to the total weight of the outer layer. The composition is preferably formulated as a bolus for veterinary use.

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