Patent References 3773921 Rumen-stable pellets Method for establishing blood levels of biocide in animals Programmed release device and method of use thereof Medication and method for treating heartworms in dogs Tablet for pharmaceutical use able to release active substances at successive times Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked Patent #: 5082669 InventorAssigneeApplicationNo. 887393 filed on 05/21/1992US Classes:424/438, Specially adapted for ruminant animal424/472, Layered unitary dosage forms424/480, Cellulose or derivative424/482Containing solid synthetic polymersExaminersPrimary: Page, Thurman K.Assistant: Phelan, D. Gabrielle Attorney, Agent or FirmForeign Patent References
International ClassA23K 001/18Foreign Application Priority Data1989-07-08 GBAbstractA solid pharmaceutical composition for release of a biologically active substance into a desired aqueous environment, containing a core and an outer layer, said core comprising between 17 and 93% by weight of the biologically active substance, between 0.01 and 7% by weight of a water swellable polymer material and between 0 and 83% of one or more accessory ingredients, relative to the total weight of the core; and the outer layer comprising between 25 and 75% by weight of the biologically active substance, between 25 and 75% by weight of a material for enabling rapid dispersion of the outer layer into the aqueous environment and 0 to 50% by weight of one or more accessory ingredients, relative to the total weight of the outer layer. The composition is preferably formulated as a bolus for veterinary use. | |