Sustained release formulations
Patent 5188836 Issued on February 23, 1993. Estimated Expiration Date: 
July 27, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 27, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMicroporous drug delivery device Retard form of pharmaceuticals with insoluble porous diffusion coatings Pharmaceutical formulations containing acrivastine Patent #: 4954350 InventorsApplicationNo. 559221 filed on 07/27/1990US Classes:424/439, Food or edible as carrier for pharmaceutical424/441, Chewable tablet or wafer424/472, Layered unitary dosage forms424/474Coated pills or tabletsExaminersPrimary: Page, Thurman K.Assistant: Phelan, D. Gabrielle Attorney, Agent or FirmInternational ClassA61K 047/00AbstractSemi-enteric controlled release formulations are comprised of a biological active agent such as an antibiotic that is blended with a water-soluble bulking agent, the mix then coated onto an inert core. The coated active core is further coated with a mixture comprised of an acrylic copolymer, bulking agent and pH dependent food acid. These different coating components possess different solubility characteristics which result in a gradual release of the active in both the stomach and small intestine that provides an increased bioavailability of the active drug. | |
