Freeze-dried dosage forms and methods for preparing the same
Patent 5188825 Issued on February 23, 1993. Estimated Expiration Date: 
February 23, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 23, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesVinylbenzyl alcohol polymer beads and thermally crosslinked derivatives thereof Confectionery delivery system for antihistimines Patent #: 4882151 InventorsApplicationNo. 458311 filed on 12/28/1989US Classes:424/78.1, Ion exchange resin424/78.08, SOLID SYNTHETIC ORGANIC POLYMER AS DESIGNATED ORGANIC ACTIVE INGREDIENT (DOAI)424/78.24, N-Vinyl-2-pyrrolidone424/78.31, Polymer from ethylenic monomers only424/78.37, Monomer contains oxygen424/439, Food or edible as carrier for pharmaceutical424/440, Candy, candy coated or chewing gum424/441, Chewable tablet or wafer424/484, Matrices424/486, Synthetic polymer426/1, BAIT, ATTRACTANT, OR PROCESS OF PREPARATION426/2, TREATMENT OF LIVE ANIMAL514/772.1, Aftertreated solid synthetic organic polymer (e.g., grafting, blocking, etc.)514/772.2, Polyvinyl alcohol514/772.3, Solid synthetic organic polymer514/772.4, Polymer from ethylenic monomers only514/777, Carbohydrate or lignin, or derivative514/778, Starch or derivative514/779, Algin or derivative514/780, Locust bean gum514/781, Cellulose or derivative514/782Natural gum or resinExaminersPrimary: Page, Thurman K.Assistant: Azpuru, Carlos Foreign Patent References
International ClassesA61K 031/74A61K 009/68 A61K 009/14 A01N 025/08 AbstractA method of preparing a freeze-dried dosage form including a water soluble active agent is disclosed. The water soluble active agent is bonded to an ion exchange resin to form a substantially water insoluble complex. This complex is then mixed with a compatible carrier and freeze-dried. The resulting freeze-dried dosage form contains an effective unit dosage amount of the active agent and exhibits enhanced compositional and physical stability, as well as permitting processing according to conventional freeze-drying techniques.Field of SearchFood or edible as carrier for pharmaceuticalCandy, candy coated or chewing gum Chewable tablet or wafer Matrices Synthetic polymer SOLID SYNTHETIC ORGANIC POLYMER AS DESIGNATED ORGANIC ACTIVE INGREDIENT (DOAI) Ion exchange resin N-Vinyl-2-pyrrolidone Polymer from ethylenic monomers only Monomer contains oxygen BAIT, ATTRACTANT, OR PROCESS OF PREPARATION TREATMENT OF LIVE ANIMAL Aftertreated solid synthetic organic polymer (e.g., grafting, blocking, etc.) Polyvinyl alcohol Polymer from ethylenic monomers only Solid synthetic organic polymer Carbohydrate or lignin, or derivative Starch or derivative Algin or derivative Locust bean gum Cellulose or derivative Natural gum or resin | |
