Apparatus and method for continuous centrifugal blood cell separation
April 1, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3899296 3901658 Centrifugal photometric analyzer Integrated fluid manipulator Simultaneous analysis apparatus Centrifugal elutriator rotor Blood cell separator Method and device for separately collecting components of a liquid by means of a centrifugal rotor Blood cell separator Method and device for bringing a liquid sample successively into contact with a number of reagents InventorsAssigneeApplicationNo. 678762 filed on 04/01/1991US Classes:210/782, Blood210/95, Sight glass210/198.1, WITH MEANS TO ADD TREATING MATERIAL210/380.1, Rotating element construction210/514, Portable invertible, e.g., milk and cream separator210/532.1, Heavier constituent trap, chamber, or recess210/789, Isolating layer422/72, Including centrifuge422/101, Including means for separating a constituent; e.g., filter, condenser, extractor, etc.436/45, Utilizing a centrifuge or compartmented rotor436/63, BIOLOGICAL CELLULAR MATERIAL TESTED436/177, Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.)436/180, Volumetric liquid transfer494/27, Liquid494/34, Having bowls spaced along common axis of rotation494/43ROTATABLE BOWLExaminersPrimary: Jones, W. GaryAttorney, Agent or FirmInternational ClassB01D 021/26AbstractAn analytical rotor for separating cellular components from a biological fluid includes a separation chamber spaced radially outward from a sample chamber. The sample chamber may be an open receptacle disposed to receive sample or may be a mixing chamber which receives sample and diluent. A flow restrictive channel connects the sample chamber to the separation chamber so that fluid enters the separation chamber at a controlled rate. The cellular components collect within a retention region located generally at the outer periphery of the collection chamber while cell-free fluid is continuously removed through a collection port. The collection port is spaced annularly apart from the flow channel so that there is sufficient residence time within the separation chamber for substantially complete separation of the cells from the fluid fraction. In a first embodiment, a collection chamber is attached through the collection port through an annular flow channel, while in a second embodiment a collection chamber is connected through a vertical flow channel.Field of SearchTransparentSight glass WITH MEANS TO ADD TREATING MATERIAL Rotating element construction With residue removing means or agitation of liquid Portable invertible, e.g., milk and cream separator TANGENTIAL FLOW OR CENTRIFUGAL FLUID ACTION Selective withdrawal of constituents Heavier constituent trap, chamber, or recess Blood Cyclonic, or centrifugal (e.g., whirling or helical motion or by vortex, etc.) Isolating layer Means is turntable (circular) Including centrifuge Including means for separating a constituent; e.g., filter, condenser, extractor, etc. Container Utilizing a centrifuge or compartmented rotor BIOLOGICAL CELLULAR MATERIAL TESTED Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.) Volumetric liquid transfer INCLUDING PLURALITY OF MINIATURE BOWLS (E.G., TEST TUBES) DISTRUBUTED ABOUT ROTATABLE CARRIER AND READILY REMOVABLE THEREFROM And means for introducing either material or auxiliary fluid into bowls Liquid Furnished at plural locations PROCESS ROTATABLE BOWL |
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