Conjugate of adriamycin and cyclodextrin
Patent 5183883 Issued on February 2, 1993. Estimated Expiration Date: 
September 27, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 27, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References14-Acyloxy-2'-halo-anthracycline anti-cancer antibiotics Patent #: 4870058 Inventors
AssigneeApplicationNo. 766791 filed on 09/27/1991US Classes:536/6.4, Daunomycin or derivative536/112Dextran or derivativeExaminersPrimary: Rollins, John W.Assistant: Peselev, Elli Attorney, Agent or FirmForeign Patent References
International ClassC07K 015/24Foreign Application Priority Data1990-09-28 JPAbstractAdriamycin derivatives represented by formula (I) ##STR1## wherein R denotes a divalent hydrocarbon group,CD denotes a cyclodextrin residue,m is 1 to 8, andn is 0 to 8.The compounds exhibit excellent anti-cancer activity over a wide administration range, have low toxicity and sustained release, and maintain activity for a long period of time; thus, they are quite useful as an anti-cancer agent.Other References
Field of SearchDextran or derivative |
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