Starch encapsulation of biologically active agents by a continuous process
Patent 5183690 Issued on February 2, 1993. Estimated Expiration Date: 
June 25, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 25, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2876160 3159585 3499962 3666557 3786123 3922354 Process of encapsulating an oil and product produced thereby Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices Starch based particulate encapsulation process Starch based encapsulation process InventorsAssigneeApplicationNo. 542566 filed on 06/25/1990US Classes:427/213.31, With post-treatment of encapsulant or encapsulating material (e.g., further coating, hardening, etc.)264/4.1, Liquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)264/4.6, Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.)264/204, Solidifying by evaporation of liquid solvent or liquid carrier264/211.11, Nonresinous material only (e.g., ceramic, soap, cellulose, etc.)264/211.12, Processing or treatment after extrusion424/493, Containing polysaccharides (e.g., sugars)424/499, Contains proteins or derivative or polysaccharides or derivative426/96, Dry flake, dry granular, or dry particulate material427/213.3Solid encapsulation process utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)ExaminersPrimary: Stoll, Robert L.Assistant: Covert, John M. Attorney, Agent or FirmForeign Patent References
International ClassesB01J 013/04A29C 047/00 A61K 009/62 A61K 009/16 AbstractBiologically active agents to be encapsulated are continuously blended with a starchy material and water, subjected to high-shear mechanical action at a temperature above the gelatinization temperature of starch, and continuously recovered as an insolubilized matrix of starch that entraps discontinuous domains of the agent. Alternatively, the core material to be encapsulated is added and blended with the aqueous dispersion of starch after the starch and water have been subjected to an elevated temperature sufficient to gelatinize the starch. Rate of release of agents to the environment can be controlled by preselecting a set of conditions related to various processing parameters. Encapsulation of biologically active compositons provides protection against degradative environmental conditions, improves safety in handling, and slows the release of such compounds to the surrounding medium.Field of SearchLiquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)With treatment subsequent to solid wall formation (e.g., coating, hardening, etc.) Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.) Solidifying by evaporation of liquid solvent or liquid carrier Nonresinous material only (e.g., ceramic, soap, cellulose, etc.) Processing or treatment after extrusion Solid encapsulation process utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome) With post-treatment of encapsulant or encapsulating material (e.g., further coating, hardening, etc.) Microcapsule with fluid core (includes liposome) Microcapsule with solid core (includes liposome) Dry flake, dry granular, or dry particulate material | |
