Patent ReferencesMicroporous-semipermeable laminated osmotic system Sustained release, comfort formulation for glaucoma therapy Patent #: 4911920 InventorsApplicationNo. 728920 filed on 07/12/1991US Classes:424/78.1, Ion exchange resin424/78.18, Polymer derived from ethylenic monomers only424/427, Ocular424/428, Bioerrodable, resorbable, or dissolving424/486, Synthetic polymer424/487, Acrylic acid and derivatives424/501, Contains solid synthetic resin514/772.6, Carboxylic acid containing monomer514/913GlaucomaExaminersPrimary: Michl, Paul R.Assistant: Webman, E. J. Attorney, Agent or FirmInternational ClassesA61K 009/10A61K 047/32 A61K 031/135 A61K 031/14 AbstractOphthalmic pharmaceutical compositions useful in controlling elevated intraocular pressure associated with glaucoma and ocular hypertension are described. The compositions comprise a combination of a beta-blocker to reduce the production of aqueous humor and carbachol to enhance the outflow of aqueous humor. A method of controlling elevated intraocular pressure with those compositions is also described.Other References
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