Isolated osteogenic factor
Patent 5169837 Issued on December 8, 1992. Estimated Expiration Date: 
March 28, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 28, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3458397 Polypeptide cartilage-inducing factors found in bone Bone morphogenetic agents Patent #: 4795804 InventorsAssigneeApplicationNo. 676179 filed on 03/28/1991US Classes:514/21, Produced by or extracted from animal tissue424/549, Skeleton (e.g., bone, teeth, etc.)530/350, PROTEINS, I.E., MORE THAN 100 AMINO ACID RESIDUES530/840Bones; tendons; teeth; cartilageExaminersPrimary: Cashion, Merrell C. Jr.Assistant: Celsa, B. Attorney, Agent or FirmInternational ClassesA61K 037/00C07K 003/00 AbstractDescribed is a purified osteogenic factor that when delivered to bone in association with a physiologically acceptable delivery vehicle is capable of inducing new bone growth at the bone surface. The osteogenic factor is water soluble, and is characterized physically by a molecular weight of about 2.5 kD when measured by gel filtration under dissociating conditions and an isoelectric point in the pH range from about 4.6 to 7.2. Use of the purified factor in treating bone defects is described. Also described is a method for obtaining the purified factor from mammalian bone.Other References
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