Directly compressible granules having improved flow properties
Patent 5169645 Issued on December 8, 1992. Estimated Expiration Date: 
December 8, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 8, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMicrofocus X-ray system Medicament adsorbates and their preparation Controlled release formulation Galenic formulations with programmed release containing naproxen Patent #: 4888178 InventorsApplicationNo. 429858 filed on 10/31/1989US Classes:424/499, Contains proteins or derivative or polysaccharides or derivative424/501, Contains solid synthetic resin424/502Contains waxes, higher fatty acids, higher fatty alcoholsExaminersPrimary: Page, Thurman K.Assistant: Spear, J. Attorney, Agent or FirmInternational ClassA61K 009/14AbstractDirectly compressible, wax-containing granules having improved flow properties are obtained when waxes are admixed in the melt with certain flow improving additives, followed by cooling and granulation of the admixture. In certain embodiments of the invention, only the wax itself melts in the melt combination of the wax(es) and additives(s), and in other cases both the wax(es) and the additives(s) will both melt. In either case, the melt combination of the wax(es) with the additive(s) yields, upon cooling and granulation, a wax-containing particulate drug diluent having improved and unexpected flow properties.Field of SearchOrganic coatingsContaining waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof (e.g., chocolate) Containing polysaccharide (e.g., sugar, etc.) Particulate form (e.g., powders, granules, beads, microcapsules, and pellets) Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof Contains waxes, higher fatty acids, higher fatty alcohols Contains solid synthetic resin Contains proteins or derivative or polysaccharides or derivative | |
