U.S. patents available from 1976 to present.
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Composition and method for enhancing the immune system in warm-blooded animals exhibiting symptoms of antigenic morbidity

Patent 5162369 Issued on November 10, 1992. Estimated Expiration Date: Icon_subject July 6, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Assignee

Application

No. 549112 filed on 07/06/1990

US Classes:

514/492, Heavy metal containing DOAI514/494, Zinc514/499, Copper514/502, Iron514/561Nitrogen other than as nitro or nitroso nonionically bonded

Examiners

Primary: Waddell, Frederick E.
Assistant: Fay, Zohreh

Attorney, Agent or Firm

International Classes

A61K 031/28
A61K 031/315
A61K 031/30
A61K 031/295

Abstract

A method for maintaining the immune system of a warm-blooded animal afflicted with a form of antigenic morbidity exacerbated by intestinal malabsorption of minerals is disclosed. Minerals selected from the group consisting of copper, zinc, manganese, iron and selenium are provided in the form of amino acid chelates having a ligand to mineral ratio of at least 1:1, a molecular weight of no more than 1500 and a stability constant of between about 106 and 1016 and administered orally. They are absorbed from a portion of the intestinal tract other than that utilized for the absorption of cations. The method is particularly adapted to the maintaining of the immune system of a warm-blooded animal infected by a virus which compromises the absorption of trace minerals via the normal cationic absorption route. The presence of intestinal malabsorption in the host showing symptoms of antigenic morbidity is first confirmed. Based on previous data of mineral levels and ratios in assayed tissues and/or body fluids of similarly infected hosts compared with mineral levels and ratios in healthy hosts, an amino acid chelate composition is formulated and administered to the afflicted animal(s) for such time as is necessary for the immune system to be properly maintained.

Other References

  • Chem Abst, 46544y (1972). Abuzarov et al
  • J. Am. Chem. Soc 1981, 103 7026-7028. Hemmi et a
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