Compositions for transdermal delivery of estradiol

Patent 5154922 Issued on October 13, 1992. Estimated Expiration Date:

May 7, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

Polymeric diffusion matrix containing estradiol diacetate
Patent #: 4291014
Issued on: 09/22/1981
Inventor: Keith , et al.

Topical corticosteroid formulations
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Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
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Matrix composition for transdermal therapeutic system
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Inventor: Leeper , et al.

Method of transdermal drug delivery
Patent #: 4624665
Issued on: 11/25/1986
Inventor: Nuwayser

Multicompartmentalized transdermal patches
Patent #: 4666441
Issued on: 05/19/1987
Inventor: Andriola , et al.

Transdermal drug patches
Patent #: 4668232
Issued on: 05/26/1987
Inventor: Cordes , et al.

Patch
Patent #: 4685911
Issued on: 08/11/1987
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Soft patch
Patent #: 4695465
Issued on: 09/22/1987
Inventor: Kigasawa , et al.

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Inventors

Assignee

Schering Corporation

Application

No. 675936 filed on 05/07/1991

US Classes:

424/448, Pressure sensitive adhesive means424/447, Bandages with incorporated medicaments424/449, Transdermal or percutaneous424/487Acrylic acid and derivatives

Examiners

Primary: Page, Thurman K.
Assistant: Phelan, D. Gabrielle

Attorney, Agent or Firm

Magatti; Anita W.

Foreign Patent References

147146 EP. 07/13/1985
250125 EP. 12/13/1987
3333240 DE. 03/13/1985
2547502 FR. 12/13/1984
8602584 WO. 06/13/1987
8707138 WO. 12/13/1987
1470355 GB. 04/13/1977
2093694 GB. 09/13/1982
2158355 GB. 11/13/1985
2185187 GB. 07/13/1987

International Class

A61F 013/02

Abstract

Solvent systems comprising oleic acid, linear alcohol lactate and either dipropylene glycol or N-methyl-2-pyrrolidine useful for preparing adhesive matrix and reservoir-type transdermal delivery devices for estradiol are disclosed.