Patent References 3677648 Measuring skin perfusion Spectrophotometric method for quantitatively determining the concentration of a dilute component in a light- or other radiation-scattering environment Apparatus for determining the concentration of a light-absorbing material in blood Substance and method for measuring hepatic blood flow Liver function testing apparatus and method Patent #: 4905703 InventorAssigneeApplicationNo. 800865 filed on 11/26/1991US Classes:600/479, Cardiovascular testing600/504Measuring blood flow in body portion other than heartExaminersPrimary: Smith, Ruth S.Attorney, Agent or FirmForeign Patent References
International ClassA61B 005/00Foreign Application Priority Data1988-09-14 JPAbstractA liver function testing apparatus measures n-times the values ƊlogT1 and ƊlogT2 corresponding to pulse wave signals obtained upon passage through a prescribed optical path in vital tissue. A sensor (30) having first and second light sources (3, 4) and a light receiving element (6) is attached to a testee (5) before injection of a specific dye. A value 댐 is calculated by using a statistical computation with two variables as to n ƊlogT1 and ƊlogT2 on the basis of an equation of ƊlogT1 =댐.ƊlogT2.ƊlogT1 and ƊlogT2 corresponding to pulse wave signals are measured in response to intensity levels of first light and second light passing through the vital tissue during a prescribed time following an injection on the basis of decision outputs representing levels of the first light and the second light from the light sources after the specific dye is injected. A value Cg corresponding to a specific dye concentration in the blood is calculated from 댐 , ƊlogT1 and ƊlogT2. A simulation curve as a function of time changes of the result of the measurements is calculated by the application of the least squares method, thereby to obtain a blood plasma disappearance rate K and a T-minute retention rate R % of the specific dye on the basis of the simulation curve.Other References
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