U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method and device for transdermally administering testosterone across nonscrotal skin at therapeutically effective levels

Patent 5152997 Issued on October 6, 1992. Estimated Expiration Date: Icon_subject February 7, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Transdermal therapeutic system having improved delivery characteristics
Patent #: 4704282
Issued on: 11/03/1987
Inventor: Campbell ,   et al.

Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols
Patent #: 4863970
Issued on: 09/05/1989
Inventor: Patel ,   et al.

Transdermal drug delivery device
Patent #: 4867982
Issued on: 09/19/1989
Inventor: Campbell ,   et al.

Externally mounted blown fuse indicator
Patent #: 4906963
Issued on: 03/06/1990
Inventor: Ackermann, et al.

Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same Patent #: 4911916
Issued on: 03/27/1990
Inventor: Cleary

Inventors

Assignee

Application

No. 652127 filed on 02/07/1991

US Classes:

424/449, Transdermal or percutaneous424/447, Bandages with incorporated medicaments424/448Pressure sensitive adhesive means

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

International Class

A61F 013/00

Abstract

Testosterone is administered transdermally through nonscrotal skin in a manner that mimics in amount and profile the natural production of testosterone in young adult healthy males. The testosterone is administered to the skin from a matrix which contains testosterone at subsaturation concentration and a permeation enhancer.

Other References

  • Korenman et al., Am. J. Med. (1987) 83:471-478
  • Ahmed et al., J. Clin. Endocrinol. Metab. (1988) 66:546-557
  • Findlay, J. Clin. Endocrinol. Metab. (1989) 68:369-37
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