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Method and apparatus for conducting electrochemiluminescent measurements Patent #: 5068088
ApplicationNo. 773971 filed on 09/27/1991
US Classes:436/149, MEASUREMENT OF ELECTRICAL OR MAGNETIC PROPERTY OR THERMAL CONDUCTIVITY422/52, Chemiluminescent422/81, Automated system with sample fluid pressure transport means435/808, OPTICAL SENSING APPARATUS436/172With fluorescence or luminescence
ExaminersPrimary: Housel, James C.
Assistant: Alexander, Lyle A.
Attorney, Agent or Firm
International ClassG01N 021/76
AbstractA method and apparatus for conducting electrochemiluminescence (ECL) measurements which control the initial conditions relating to the surface state of a triggering working electrode by reproducibly creating and maintaining a favorable surface condition so as to enhance the precision and detection limit of the measurements. Assays are performed with ECL detection in a flow-through cell environment and the precision and detection limit are enhanced by alternating initialization and measurement steps.