U.S. patents available from 1976 to present.
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Eye drop formulation useful for treating lesions of corneal epithelium

Patent 5145680 Issued on September 8, 1992. Estimated Expiration Date: Icon_subject October 9, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventor

Assignee

Application

No. 594094 filed on 10/09/1990

US Classes:

424/427, Ocular424/422, Implant or insert514/8, Glycoprotein (carbohydrate containing)514/912, OPHTHALMIC514/914, Inflammation514/915, Wetting agent530/395, Glycoprotein, e.g., mucins proteoglycans, etc.530/830Plasma; serum

Examiners

Primary: Page, Thurman K.
Assistant: Azpuru, Carlos

Attorney, Agent or Firm

Foreign Patent References

  • 0179477 EP. 04/21/1986
  • 240031 EP. 10/21/1987
  • 292663 EP. 11/21/1988

International Classes

C07K 001/02
C07K 015/06

Foreign Application Priority Data

1989-02-13 JP

Abstract

Vitronectin produces very high therapeutic effects upon injuries of the corneal epithelium. When applied to lesions of the corneal epithelium in the form of eye drops, Vitronectin induces rapid cure of the lesions with regeneration of normal cells. Moreover Vitronectin can be sterilized by autoclaving.

Other References

  • "Effect of vitronectin on the healing of rabbit corneal epithelial damage", Kabata et al., Nippon Ganka Gakkai Zasshi (Japan), May 1990, 94(5) pp. 457-461 (Abstract) Abstract onl
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