U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Capillary flow device

Patent 5140161 Issued on August 18, 1992. Estimated Expiration Date: Icon_subject July 23, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3720097

3799742

Use of laser speckle patterns for measurement of electrophoretic mobilities
Patent #: 4011044
Issued on: 03/08/1977
Inventor: Uzgiris

Apparatus for sampling, mixing the sample with a reagent and making particularly optical analyses
Patent #: 4088448
Issued on: 05/09/1978
Inventor: Lilja, et al.

Apparatus for measuring the aggregation rate of particles
Patent #: 4135819
Issued on: 01/23/1979
Inventor: Schmid-Schonbein

Method of measuring the fluidity of liquids for medical and pharmaceutical purposes, and apparatus for performing the method
Patent #: 4165632
Issued on: 08/28/1979
Inventor: Weber ,   et al.

Liquid transport device and method
Patent #: 4233029
Issued on: 11/11/1980
Inventor: Columbus

Photometric method for determining courses of reactions
Patent #: 4492462
Issued on: 01/08/1985
Inventor: Pross ,   et al.

Apparatus for determining the flow shear stress of suspensions in particular blood
Patent #: 4519239
Issued on: 05/28/1985
Inventor: Kiesewetter ,   et al.

Capillary flow device
Patent #: 4756884
Issued on: 07/12/1988
Inventor: Hillman ,   et al.

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Inventors

Assignee

Application

No. 734597 filed on 07/23/1991

US Classes:

250/341.3, Including polarizing means73/64.43, By optical measurement422/947, Using capillary action, including fluid transfer through absorbent matrix [B01L 3/00C6C]436/69CLOTTING OR CLOTTING FACTOR LEVEL TESTS

Examiners

Primary: Howell, Daniel W.
Assistant: Hanig, Richard

Attorney, Agent or Firm

Foreign Patent References

  • 2007405 DE. 02/13/1970
  • 3134611Al DE. 09/13/1981
  • 376300 SE. 09/13/1976

International Classes

G01N 021/49
G01N 031/22

Abstract

Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastics devices is also described along with various control devices for use with the basic device.

Other References

  • "A Light-Scattering Apparatus for the Study of Cellular Suspensions", Powers et al., Biomedical Engrg. BME-30:228-231 (Jan. 1983)
  • "Size Distribution Measurements of Microaggregates in Stored Blood", Reynolds et al., Transfusion, 20 (6):669-678 (Nov.-Dec. 1980)
  • "Laying the Groundwork for Ultrasonic Welding", Plastics Engineering, pp. 85-87 (Aug. '1985
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