Pharmaceutical compositions with anti-cancer activity against carcinoma and method for the treatment of carcinoma
Patent 5135948 Issued on August 4, 1992. Estimated Expiration Date: 
September 12, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 12, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 581110 filed on 09/12/1990US Classes:514/467, Only two ring oxygens in the hetero ring which is not a polycyclo ring system (e.g., dioxolane, etc.)514/474Ascorbic acid or derivative (e.g., vitamin C, etc.)ExaminersPrimary: Goldberg, Jerome D.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/335A61K 031/34 AbstractThe use of L-ascorbic acid, or a pharmaceutically acceptable salt thereof, in combination with 5,6-O-benzylidene-L-ascorbic acid, or 5,6-O-benzylidene-L-ascorbic acid deuterated at least at the 1-position of the aldehyde group of the benzylidene moiety, or a pharmaceutically acceptable salt of such acids, results in a synergistically enhanced cytotoxicity on human carcinoma cells.Other References
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