Pharmaceutical preparations containing cyclodextrin derivatives Patent #: 4727064
ApplicationNo. 173305 filed on 03/25/1988
US Classes:514/56, Heparin or derivative514/24, S-glycoside514/58, Dextrin or derivative514/475The hetero ring is three-membered
ExaminersPrimary: Griffin, Ronald W.
Assistant: Webber, Pamela S.
Attorney, Agent or Firm
International ClassesA61K 031/715
AbstractFumagillin and its salts have an angiogenesis inhibiting activity and are useful for prophylaxis and treatment of diseases induced by abnormally stimulated neovascularization. The invention also provides certain pharmaceutical compositions comprising fumagillin or its salt, and an agent which potentiates angiogenesis inhibition such as heparin and sulfated cyclodextrins such as beta-cyclodextrin tetradecasulfate.