U.S. patents available from 1976 to present.
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Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof

Patent 5134127 Issued on July 28, 1992. Estimated Expiration Date: Icon_subject January 23, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3426011

3816393

Inclusion compound of lankacidin-group antibiotic and use thereof
Patent #: 4497803
Issued on: 02/05/1985
Inventor: Harada ,   et al.

Water soluble cyclodextrin polymers substituted by ionic groups and process for the preparation thereof
Patent #: 4535152
Issued on: 08/13/1985
Inventor: Szejtli ,   et al.

Inclusion complex of ଲ-cyclodextrin and digoxin
Patent #: 4555504
Issued on: 11/26/1985
Inventor: Jones

Water-soluble mixed ethers of ଲ-cyclodextrin and a process for their preparation
Patent #: 4582900
Issued on: 04/15/1986
Inventor: Brandt ,   et al.

Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
Patent #: 4596795
Issued on: 06/24/1986
Inventor: Pitha

Ethers of beta-cyclodextrin and a process for their preparation
Patent #: 4638058
Issued on: 01/20/1987
Inventor: Brandt ,   et al.

Pharmaceutical preparations containing cyclodextrin derivatives
Patent #: 4727064
Issued on: 02/23/1988
Inventor: Pitha

Partially methylated cyclodextrins and process for producing the same
Patent #: 4746734
Issued on: 05/24/1988
Inventor: Tsuchiyama ,   et al.

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Inventors

Assignee

Application

No. 469087 filed on 01/23/1990

US Classes:

514/58, Dextrin or derivative514/778, Starch or derivative514/964, SUSTAINED OR DIFFERENTIAL RELEASE TYPE514/965, Discrete particles in supporting matrix536/103Dextrin or derivative

Examiners

Primary: Griffin, Ronald W.

Attorney, Agent or Firm

International Classes

C08B 037/16
A61K 031/71
A61K 031/715

Abstract

Sulfoalkyl ether cyclodextrin derivatives and their use as solubilizing agents for water insoluble drugs for oral, intranasal, or parenteral administration are disclosed.

Other References

  • Proceedings of the Fourth International Symposium on Cyclodextrins, (1988) pp. 369-382, "Cyclodextrin Derivatives for Solubilisation, Stabilisation, and Absorption of Drugs" B. W. Mueller et al
  • Third International Symposium on Recent Advances in Drug Delivery Systems, (1987), pp. 1-12, "Amorphous Water Soluble Derivatives of Cyclodextrins: From Test Tube to Patient", Josef Pith
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