U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Extended release pharmaceutical formulations

Patent 5133974 Issued on July 28, 1992. Estimated Expiration Date: Icon_subject January 24, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3623997

Fungimycin compositions
Patent #: 4000254
Issued on: 12/28/1976
Inventor: Gordon ,   et al.

New oral form of medicament and a method for producing it
Patent #: 4083949
Issued on: 04/11/1978
Inventor: Benedikt

Sustained release indomethacin
Patent #: 4173626
Issued on: 11/06/1979
Inventor: Dempski ,   et al.

Controlled release tablet
Patent #: 4252786
Issued on: 02/24/1981
Inventor: Weiss ,   et al.

Super-fast-starting-sustained release tablet
Patent #: 4503031
Issued on: 03/05/1985
Inventor: Glassman

Drug delivery device
Patent #: 4592753
Issued on: 06/03/1986
Inventor: Panoz

New pharmaceutical forms for administration of medicaments by oral route, with programmed release
Patent #: 4609542
Issued on: 09/02/1986
Inventor: Panoz ,   et al.

Controlled release formulation
Patent #: 4610870
Issued on: 09/09/1986
Inventor: Jain ,   et al.

Preparation of nitroesters for coronary artery therapy
Patent #: 4611008
Issued on: 09/09/1986
Inventor: Heinzelmann

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Inventors

Application

No. 469210 filed on 01/24/1990

US Classes:

424/480, Cellulose or derivative424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/456, Gelatin424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/474, Coated pills or tablets424/475, Organic coatings424/494, Cellulose derivatives514/960, SIGNIFICANT, TABLET FORMULATION (E.G., DESIGNATED EXCIPIENT, DISINTEGRANT, GLYDENT OR LUBRICANT, ETC.)514/961, Binder therefor514/962, CAPSULE (E.G., GELATIN, ETC.)514/963, Microcapsule-sustained or differential release514/964SUSTAINED OR DIFFERENTIAL RELEASE TYPE

Examiners

Primary: Page, Thurman K.
Assistant: Harrison, Robert H.

Attorney, Agent or Firm

Foreign Patent References

  • 1183665 CA. 03/13/1985
  • 3048119 EP. 03/13/1984
  • 0122077 EP. 10/13/1984
  • 843019548 EP. 10/13/1984
  • 325843 EP. 08/13/1989
  • 8500481 WO. 03/13/1986
  • 1182124 GB. 02/13/1970
  • 1245467 GB. 09/13/1971
  • 2098867 GB. 12/13/1982
  • 2141342 GB. 12/13/1984
  • 2159715 GB. 12/13/1985

International Class

A61K 009/36

Abstract

An extended release pharmaceutical formulation adapted to approach zero order release of drug over a 12 to at least 24 hour period, comprised of a mixture of 0 to aobut 50% of an immediate release particle containing a drug, inert substrate and binder, coated with talc and up to 100% of an extended release particle comprising the immediate release particle coated with a dissolution modifying system containing plasticizers and a film forming agent.

Other References

  • The Dow Chemical Company "Formulating for Controlled Release with METHOCEL cellulose ethers" 1987
  • Copies of the PTO-1449 Forms as filed in the parent case (P6523
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