U.S. patents available from 1976 to present.
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2-thienylglycidic derivative, process for its preparation and its use as synthesis intermediate

Patent 5132435 Issued on July 21, 1992. Estimated Expiration Date: Icon_subject July 2, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Assignee

Application

No. 724988 filed on 07/02/1991

US Classes:

549/60, Ring oxygen in the additional hetero ring546/114, Ring sulfur in the bicyclo ring system549/75Chalcogen attached indirectly to the hetero ring by nonionic bonding

Examiners

Primary: Dentz, Bernard

Attorney, Agent or Firm

Foreign Patent References

  • 0069002 EP. 01/13/1983

International Classes

C07D 407/04
C07D 333/22
C07D 495/04

Foreign Application Priority Data

1990-07-04 FR

Abstract

The invention relates to isopropyl 2-thienylglycidate of formula: ##STR1## obtained by reaction of 2-thienylcarboxaldehyde with an isopropyl haloacetate. It is employed as a synthesis intermediate in the preparation of 2-thienylacetaldoxime and of medications derived from thieno[3,2-c]pyridine.

Other References

  • Dullaghan et al., I, J. O. C., 17, pp. 1183-1186 (1952)
  • Dullaghan et al., II, J. O. C., 18, pp. 878-881 (1953)
  • Patent Abstracts of Japan, vol. 11, No. 317, (C-452) (2764), Oct. 15, 1987; & JP-A-62 103 087, (Toyo Pharma K.K.), May 15, 1987
  • Chemical Abstracts of Japan, vol. 89, No. 3, Jul. 17, 1978, p. 650; & JP-A-53 07 687, (Sanwa Chemical Laboratories), Jan. 24, 197
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