U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Controlled release tablet containing water soluble medicament

Patent 5126145 Issued on June 30, 1992. Estimated Expiration Date: Icon_subject June 11, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3870790

Method and composition for the preparation of controlled long-acting pharmaceuticals
Patent #: 4259314
Issued on: 03/31/1981
Inventor: Lowey

Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
Patent #: 4369172
Issued on: 01/18/1983
Inventor: Schor ,   et al.

Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
Patent #: 4389393
Issued on: 06/21/1983
Inventor: Schor ,   et al.

Method and composition for the preparation of controlled long-acting pharmaceuticals for oral administration
Patent #: 4680323
Issued on: 07/14/1987
Inventor: Lowey

Controlled release formulation Patent #: 4756911
Issued on: 07/12/1988
Inventor: Drost ,   et al.

Inventors

Application

No. 536184 filed on 06/11/1990

US Classes:

424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/470, Where particles are granulated424/488, Polysaccharides (e.g., cellulose, etc.)424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/499, Contains proteins or derivative or polysaccharides or derivative424/502, Contains waxes, higher fatty acids, higher fatty alcohols514/960, SIGNIFICANT, TABLET FORMULATION (E.G., DESIGNATED EXCIPIENT, DISINTEGRANT, GLYDENT OR LUBRICANT, ETC.)514/964SUSTAINED OR DIFFERENTIAL RELEASE TYPE

Examiners

Primary: Page, Thurman K.
Assistant: Spear, James M.

Foreign Patent References

  • 0109320 FR. 06/13/1986

International Classes

A61K 009/20
A61K 009/22

Abstract

A sustained or controlled release tablet is disclosed. The tablet comprises a water soluble medicament, a hydroxypropyl methylcellulose having sustaining action, a pharmaceutical binding agent, and a hydrophobic component.

Other References

  • Methocel as a Binding Agent for Tablet Production by Wet Granulation, Dow Chemical U.S.A., 1985
  • Formulating for Controlled Release with Methocel Cellulose Ethers, Dow Chemical U.S.A., 198
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