Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides
August 10, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3640741 3847155 Method of immunodiffusion Appetite curbing preparation containing an alginate and a diphosphonic acid Surgical gloves and surface treatment of surgical gloves for avoiding starch peritonitis and the like Methods for temporomandibular joint small incision surgery Gelatin-encapsulated controlled-release composition Preparation of a gel having gas transporting capability Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator Chitosan compositions for controlled and prolonged release of macromolecules InventorAssigneeApplicationNo. 565770 filed on 08/10/1990US Classes:424/423, Surgical implant or material424/78.37, Monomer contains oxygen424/427, Ocular424/431, Tampon514/944GELExaminersPrimary: Page, Thurman K.Assistant: Webman, E. J. Attorney, Agent or FirmInternational ClassesA61K 009/107A61K 047/34 A61K 047/36 AbstractA process and compositons for reducing post-surgical adhesion formation/reformation in mammals following injury to organs situated in mammalian body spaces. Aqueous, thermally reversible gel compositions, preferably at mammalian body fluid pH, comprising a polyoxyalkylene polymer and an ionic polysaccharide are applied to injured areas of the organs situated in body cavities such as, the peritoneal, pelvic, or pleural cavity. The aqueous gels are rendered thermally irreversible upon contact with a counter-ion.Other References
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